Quantitative ultrasound (QUS) continues to mature as a research field and is primed to make a swift transition to routine preclinical and clinical applications. This book will serve two main purposes:

Advanced education in QUS by providing a complete and thorough review of all theoretical, physical, and engineering aspects of QUS.Review of recent development of QUS by lead contributors in the research field.

This 2nd edition will focus on 6 modern research topics related to quantitative ultrasound of soft tissues:

Spectral-based methods for tissue characterization, tissue typing, cancer detection, etc.Attenuation estimation for tissue characterization and improving spectral based methodsEnvelope statistics analysis as a means of quantifying and imaging tissue properties.Ultrasound computed tomography for preclinical and clinical imaging.Scanning acoustic microscopy for formingimages of mechanical properties of soft tissues with micron resolution.Phantoms for quantitative ultrasound.

Dr. Jonathan Mamou graduated in 2000 from the Ecole Nationale Supérieure des Télécommunications in Paris, France. In January 2001, he began his graduate studies in Electrical and Computer Engineering at the University of Illinois in Urbana-Champaign, Urbana, IL. He received his M.S. and Ph.D. degrees in May 2002 and 2005, respectively. He previously was the Associate Research Director of the F. L. Lizzi Center for Biomedical Engineering at Riverside Research in New York, NY. He currently holds a faculty position in the Department of Radiology of Weill Cornell Medicine in New York, NY. Dr. Mamou also is an Adjunct Professor in the Department of Electrical Engineering of New York University. His fields of interest include theoretical aspects of ultrasound scattering, ultrasonic medical imaging, quantitative acoustic microscopy, ultrasound contrast agents, and biomedical image processing. Dr. Mamou is a Fellow of the American Institute of Ultrasound in Medicine (AIUM), a Seniormember of IEEE, and a member of the Acoustical Society of America. He is coeditor of the book Quantitative Ultrasound in Soft Tissues published by Springer, in 2013. In 2022, he was inducted into the Council of Distinguished Investigators of the Academy for Radiology& Biomedical Imaging. He served as the Chair of the AIUM High-Frequency Clinical and Preclinical Imaging Community of Practice. He is an Associate Editor of Ultrasonic Imaging and the IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, and a reviewer for numerous journals.

Michael L. Oelze was born in Hamilton, New Zealand, in 1971. He received the B.S. degree in physics and mathematics from Harding University, Searcy, AR, USA, in 1994, and the Ph.D. degree in physics from the University of Mississippi, Oxford, MS, USA. From 2000 to 2002, he was a Post-Doctoral Researcher with the Bioacoustics Research Laboratory, Department of Electrical and Computer Engineering (ECE), University of Illinois at Urbana Champaign (UIUC), Urbana, IL, USA. From 2002 to 2004, he was an NIH Fellow conducting research in quantitative ultrasound techniques for biomedical ultrasound applications in cancer detection. He is currently a Professor and the Associate Head for Graduate Affairs in ECE at UIUC, the Frederick and Elizabeth Nearing Scholar in the Grainger College of Engineering and a Health Innovator Professor in the Carle Illinois College of Medicine. His research interests include biomedical ultrasound, quantitative ultrasound imaging for improving cancer diagnostics and monitoring therapy response, ultrasound bioeffects, ultrasound tomography techniques, ultrasound-based therapy, beamforming, and ultrasound-based medical implants. Dr. Oelze is currently a Fellow of the AIUM, and a member of ASA. He is a member of the Technical Program Committee of the IEEE Ultrasonics Symposium. He currently serves as an Associate Editor of IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, for Ultrasonic Imaging, and for IEEE Transactions on Biomedical Engineering. 

 

Preface.- Part I: Backscatter Coefficient methods.- Chapter 1. Quantitative Ultrasound: an Emerging Technology for Detecting, Diagnosing, Imaging, Evaluating, and Monitoring Disease (Ernie Feleppa).- Chapter 2. Quantitative Ultrasound: Scattering theory (Michael Oelze).- Chapter 3. Quantitative Ultrasound: Experimental implementation (Michael Oelze).- Chapter 4. Extracting Quantitative Ultrasonic Parameters from the Backscatter Coefficient (Aiguo Han).- Part II: Attenuation Estimation Methods.- Chapter 5. Attenuation Compensation and Estimation (Timothy Bigelow and Yassin Labyed).- Chapter 6. Recent advances in attenuation estimation (Ivan Rosado Mendez).- Part III: Envelope Statistics Methods.- Chapter 7. Review of envelope statistics models for quantitative ultrasound imaging and tissue characterization (Francois Destrempes and Guy Cloutier).- Chapter 8. Information entropy and its applications (Po-Hsaing Tsui).- Part IV: Ultrasound Computed Tomography.- Chapter 9. Ultrasound Tomography (Nicole Ruiter, Torsten Hopp, Michael Zapf and Hartmut Gemmek).- Chapter 10. Full Wave Inversion and Inverse Scattering in Ultrasound Tomography/Volography (James Wiskin).- Chapter 11. Clinical Importance of 3D Volography in Breast Imaging (John Klock).- Part V: Acoustic microcopy.- Chapter 12. Acoustic Microscopy (Yoshifumi Saijo).- Chapter 13. Advanced Topics in Quantitative Acoustic Microscopy (Cameron Hoerig and Jonathan Mamou).- Part VI: Phantoms for Quantitative Ultrasound.- Chapter 14. Phantoms for Quantitative Ultrasound (Tim Stiles).- Index.