Wallace has spent his summer in the lab breeding a strain of microscopic worms. He is four years into a biochemistry degree at a Midwestern university, a life that's a world away from his childhood in Alabama. His father died a few weeks ago, but Wallace didn't go back for the funeral, and he hasn't told his friends. For reasons of self-preservation, he has become used to keeping a wary distance even from those closest to him. But, over the course of one blustery weekend, the destruction of his work and a series of intense confrontations force Wallace to grapple with both the trauma of the past, and the question of the future.